About this programme
R1 Capital is a venture firm based in Columbus, Ohio, that partners with founders building companies in AI-enabled software, applied technologies, and life sciences. It focuses on companies solving complex, real-world problems in undercapitalized markets.
R1 Capital works alongside Rev1 Ventures' startup studio, which prepares high-growth companies for capital raises through hands-on programming and mentorship. R1 Capital is the investment partner fund that follows on from that studio work.
The firm has supported more than 150 startups over the past decade and has invested in over 40 companies including Clarametyx, HubiFi, Redi Health, STAQ Pharma, and Power to Hydrogen, spanning software and life sciences.
How it works
R1 Capital invests across creation, validation, and growth stages, typically writing checks of $250,000 to over $1 million per company.
Beyond capital, the firm provides network access, operating resources, hands-on support, introductions to other investors, and help preparing for investor conversations.
R1 Capital has Midwest roots but operates with a national reach.
Who can apply
Priority goes to founders in the Columbus region and the broader Midwest.
The firm focuses on software, life sciences, and advanced-technology startups at the pre-seed through early stage.
How to apply
- Reach out through the contact form at r1funds.com/contact/ to start a conversation with the R1 Capital team.
Frequently asked
How much does R1 Capital typically invest?
Checks typically range from $250,000 to over $1 million per company.
What sectors does R1 Capital focus on?
AI-enabled software, applied technologies, and life sciences, particularly companies solving complex problems in undercapitalized markets.
Does R1 Capital only invest in Columbus-based companies?
Priority goes to founders in the Columbus region and the broader Midwest, though the firm has a national presence.
What does R1 Capital offer besides money?
Network access, operating resources, hands-on support, introductions to other investors, and help preparing for investor conversations.
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Reviewed 2026-09-25. Programmes change, so check eligibility, amounts and deadlines on the official page before you apply. CapEasy is a private firm and is not part of any government body.