United States / Funding / By state / South Carolina

Funding for startups in South Carolina

South Carolina runs 10 programmes of its own, and 8 of them take applications right now. The 63 federal programmes further down are open to South Carolina companies too. We read each one on its official site and note the date we checked.

Run by South Carolina and local bodies

Loan

CommunityWorks Carolina Small and Microbusiness Loans

CommunityWorks Carolina · South Carolina

Small and micro business loans plus coaching from a Greenville-based CDFI serving South Carolina.

Open nowChecked Sep 24, 2026
Loan

SC Community Loan Fund Small Business Lending

South Carolina Community Loan Fund · South Carolina

Business loans from a South Carolina CDFI for acquisition, renovation, equipment, and working capital.

Open nowChecked Sep 24, 2026
Equity

SC Launch Inc.

SC Launch Inc. (South Carolina Research Authority) · South Carolina

Convertible loans or equity investment from SCRA's investment affiliate for South Carolina technology companies.

Open nowChecked Sep 24, 2026
Up to $25kGrant

SCRA Academic Startup Grant

South Carolina Research Authority (SCRA) · South Carolina

Grants up to $25,000 for South Carolina startups commercializing university intellectual property.

Open nowChecked Sep 24, 2026
Up to $50kGrant

SCRA Acceleration Grant

South Carolina Research Authority (SCRA) · South Carolina

Grants up to $50,000 to help established early-stage South Carolina companies mature toward an SC Launch investment.

Open nowChecked Sep 24, 2026
Up to $50kGrant

SCRA Federal Matching Grant

South Carolina Research Authority (SCRA) · South Carolina

Up to $50,000 matching South Carolina startups that already won a Federal SBIR/STTR-type commercialization grant.

Open nowChecked Sep 24, 2026
Up to $25kGrant

SCRA Startup Grant

South Carolina Research Authority (SCRA) · South Carolina

Grants up to $25,000 for early-stage South Carolina technology companies pursuing commercialization milestones.

Open nowChecked Sep 24, 2026
Equity

VentureSouth

VentureSouth · South Carolina

Angel investor network based in Greenville funding pre-seed and seed startups through a monthly pitch process.

Open nowChecked Sep 24, 2026
Support

Drive Accelerator Program

SCbio · South Carolina

Twice-yearly biotech accelerator with mentoring and in-kind prizes for South Carolina and Massachusetts therapeutics startups.

Opens in roundsChecked Sep 24, 2026
Grant

SCRA Tech Catalyst Fund

South Carolina Research Authority (SCRA) · South Carolina

Non-dilutive funding for early-stage medtech startups improving rural health access in South Carolina.

Not yet confirmedChecked Sep 24, 2026

Want to filter these by amount or stage? Open them in the full directory.

Federal programmes open to South Carolina businesses

Grants 23

Loans & guarantees 15

Tax benefits 8

Equity 7

Support & credits 10

The other South Carolina deadline funders will ask about

Most programmes above ask for financials and a company in good standing. In South Carolina that means the annual report — No recurring report exists for a standard SC LLC.

South Carolina annual-report deadline & fee →

This page exists because South Carolina has at least 2 verified programmes of its own. See every state, or tell us about a South Carolina programme we are missing via the contact page.

Funders read the books before the pitch

Every programme on this page asks for financials in a particular shape. We keep South Carolina books in that shape year-round, so applying is an export rather than a rebuild.

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