United States / Funding / By state / Massachusetts

Funding for startups in Massachusetts

Massachusetts runs 14 programmes of its own, and 9 of them take applications right now. The 63 federal programmes further down are open to Massachusetts companies too. We read each one on its official site and note the date we checked.

Run by Massachusetts and local bodies

Up to $2MGrant

Business Builds: Life Sciences

Massachusetts Life Sciences Center (MLSC) · Massachusetts

Massachusetts Life Sciences Center grants $500,000 to $2 million, 50/50 matched, to life sciences companies expanding manufacturing in the state.

Open nowChecked Sep 24, 2026
Up to $75kGrant

Catalyst Program

MassVentures, jointly administered with Massachusetts Clean Energy Center (MassCEC) · Massachusetts

MassVentures and MassCEC give up to $75,000 to Massachusetts early-stage clean energy companies and researchers building first prototypes.

Open nowChecked Sep 24, 2026
Loan

Elevate Small Business

LEAF (Local Enterprise Assistance Fund) · Massachusetts

LEAF, a Massachusetts nonprofit lender, offers small business loans and advice to underserved entrepreneurs and cooperatives statewide.

Open all yearChecked Sep 24, 2026
Up to $4MLoan

Emerging Technology Fund

MassDevelopment · Massachusetts

MassDevelopment lends up to $4 million to Massachusetts technology companies for equipment, real estate, or working capital as they expand.

Open all yearChecked Sep 24, 2026
Up to $100kLoan

Growth Capital Microloan Program

MassDevelopment · Massachusetts

MassDevelopment lends $5,000 to $100,000 to Massachusetts small businesses operating at least a year, including childcare businesses.

Open all yearChecked Sep 24, 2026
Up to $350kGrant

InnovateMass

Massachusetts Clean Energy Center (MassCEC) · Massachusetts

MassCEC funds up to $350,000 for Massachusetts clean energy companies piloting new technology with a demonstration project partner.

Open nowChecked Sep 24, 2026
Equity

MassVentures Deep Tech Venture Fund

MassVentures · Massachusetts

MassVentures makes equity investments in Massachusetts seed-stage deep tech startups, often academic spinouts, alongside private co-investors.

Open all yearChecked Sep 24, 2026
Up to $250kLoan

SBIR Bridge Loan (Emerging Technology Fund)

MassDevelopment · Massachusetts

MassDevelopment advances up to $250,000, 90% of milestone payments, to Massachusetts SBIR grant recipients waiting on federal funds.

Open all yearChecked Sep 24, 2026
Up to $8kGrant

Small Business Enhancement Program

City of Cambridge Community Development Department · Massachusetts

Cambridge reimburses eligible retail, food, home-based, and creative businesses up to $8,000 for equipment and materials purchases.

Open nowChecked Sep 24, 2026
Up to $65kGrant

Innovation Challenge

Berthiaume Center for Entrepreneurship, Isenberg School of Management, UMass Amherst · Massachusetts

UMass Amherst's Berthiaume Center awards up to $65,000 in equity-free prize money to current students and recent graduates each spring.

Opens in roundsChecked Sep 24, 2026
Up to $25kGrant

MIT Sandbox

MIT Sandbox (Martin Trust Center for MIT Entrepreneurship) · Massachusetts

MIT gives its students up to $25,000 in non-dilutive funding per team across three application cycles a year.

Opens in roundsChecked Sep 24, 2026
Up to $75kGrant

President's Innovation Challenge

Harvard Innovation Labs · Massachusetts

Harvard Innovation Labs awards up to $75,000 in non-dilutive grants to Harvard student and alumni ventures each year.

Opens in roundsChecked Sep 24, 2026
Up to $500kGrant

MassVentures START Program

MassVentures (quasi-public, Commonwealth of Massachusetts) · Massachusetts

Non-dilutive commercialization grant for Massachusetts companies with a federal SBIR Phase II award; next application window opens Feb 1, 2027.

Closed until next roundChecked Aug 14, 2026
Up to $75kLoan

Small Business Grant Program

City of Worcester Business and Community Development · Massachusetts

Worcester offers forgivable loans of $25,000 to $75,000 to new or expanding storefront small businesses in targeted commercial corridors.

Not yet confirmedChecked Sep 24, 2026

Want to filter these by amount or stage? Open them in the full directory.

Federal programmes open to Massachusetts businesses

Grants 23

Loans & guarantees 15

Tax benefits 8

Equity 7

Support & credits 10

The other Massachusetts deadline funders will ask about

Most programmes above ask for financials and a company in good standing. In Massachusetts that means the Annual Report — Due on or before the anniversary of the date the original certificate of organization was filed.

Massachusetts annual-report deadline & fee →

This page exists because Massachusetts has at least 2 verified programmes of its own. See every state, or tell us about a Massachusetts programme we are missing via the contact page.

Funders read the books before the pitch

Every programme on this page asks for financials in a particular shape. We keep Massachusetts books in that shape year-round, so applying is an export rather than a rebuild.

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